I went to eat some of the ginger and it was so intense! Enter your email address to receive notifications. : it’s generally not a problematic plant). Total synthesis of zerumbone, … cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and …, The chemistry of zerumbone. This study evaluated in vitro antioxidant potential of Z. zerumbet rhizome ethyl acetate extract on hydrogen peroxide (H 2 O 2)-induced red blood cells (RBCs) damage; by measuring percentage of haemolysis, oxidative damage and Check with your pharmacist for more details about the particular brand you use.The FDA has not reviewed this product for safety or effectiveness. Simplified isolation, conjugate addition reactions, and a unique ring contracting transannular reaction of its dibromide, Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells, Zerumbone abolishes RANKL-induced NF-κB activation, inhibits osteoclastogenesis, and suppresses human breast cancer–induced bone loss in athymic nude mice, Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway, Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer, Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human HeLa cervical cancer cells, The chemistry of zerumbone. Cisplatin, was used as a positive control in this study. Perhaps the most well known use … 5.3 Zingiber zerumbet. Zingiber Zerumbet-Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. These findings support the use in Thai traditional medicine of these selected Zingiberaceous plants, especially Kaempferia parviflora and Zingiber cassumunar, for treatment of allergy and allergic-related diseases. 2 Amaranthaceae - Anacardiaceae. ive heard of people freezing it. Bot. 2. In the family Zingiberaceae, this fragrant ornamental perennial has leafy stems growing from a forked (sympodial) underground, fleshy rhizome-stem. Prevents cancer development. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials: A Review, Antiproliferative and antiangiogenic effects of zerumbone from Zingiber zerumbet L. Smith in sprague dawley rat model of hepatocellular carcinoma, Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide, INHIBITORY EFFECT OF ZERUMBONE ON MIGRATION OF COLORECTAL CANCER CELLS VIA DOWN-REGULATION OF MATRIX METALLOPROTEINASE-13 …, Molecular docking, MD simulation, DFT and ADME-toxicity study on analogs of zerumbone against IKK-β enzyme as anti-cancer agents, Prophylactic and Therapeutic Efficacies of Dietary Zerumbone Supplementation on the Pathogenesis of Atherosclerosis in Cholesterol-fed Rabbits, ANTI-LEUKEMIC EFFECTS OF ZERUMBONE NANOPARTICLE ON HUMAN LYMPHOBLASTIC LEUKEMIA CELLS (JURKAT) IN VITRO AND MURINE …, Lewis-Acid-Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC PROPERTIES OF ZERUMBONE AND THEIR MECHANISMS OF ACTION IN MICE MODEL OF NEUROPATHIC …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF ZERUMBONE THROUGH INVOLVEMENT OF MONOAMINERGIC PATHWAYS IN MICE MODEL …, COMPARISON STUDY OF THE EFFECTS OF ZERUMBONE AND AG490 IN HUMAN RENAL CELL CARCINOMA ON THE ACTIVATION OF THE JANUS KINASE …, CYTOTOXICITY AND MECHANISMS OF ACTION OF ZERUMBONE-LOADED NANOSTRUCTURED LIPID CARRIER IN TRIPLE NEGATIVE BREAST CANCER …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITIES OF ZERUMBONE IN CHRONIC CONSTRICTION INJURY-INDUCED NEUROPATHIC PAIN AND …, Potential chemoprevention of dimethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, … Obat Antikanker Payudara dari Lempuyang Gajah dan Lempuyang Emprit dengan Kontrol Kualitas Berbasis Senyawa Penanda Zerumbone dan Aktivitas Antikanker …, Zerumbone Protects against Carbon Tetrachloride (CCl4)-Induced Acute Liver Injury in Mice via Inhibiting Oxidative Stress and the Inflammatory Response: Involving …, … of ATF3 for ER Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to TRAIL-mediated Apoptosis Through Upregulation of DR5 by Zerumbone …, Study on transformation of zerumbone with fatty acid hydrazides, Hormetic Effects of Zerumbone in Proteostasis, Zerumbone 처리에 따른 Helicobacter pylori 의 단백질 비교분석, CYTOTOXICTY OF ZERUMBONE AGAINST LIVER CANCER CELL LINES (HepG2) VIA APOPTOSIS ACTIVITY, Comparative Proteome Analysis of Zerumbone-treated Helicobacter pylori, Nghiên cứu các phương pháp phân lập Zerumbone có chất lượng cao từ thân rễ cây gừng gió (zingiber zerumbert sm.) Zingiber darceyi H.J.Veitch. L'utilisation la plus commune du Zingiber zerumbet est en soin capillaire comme shampooing ou conditionneur. Zerumbone was also found to inhibit the proliferation of non-malignant Chang Liver and MDBK cell lines. 2: 105, t. 112. for pharmaceutical and cosmeceutical industry, Molecular Mechanisms of Inhibitory Effect of Zerumbone on Human Malignant Melanoma Cells, Evaluation of cytotoxic and genotoxic effects of zerumbone on colon adenocarcinoma colo205 cells and human lymphocytes, Dietary zerumbone, a sesquiterpene, ameliorates hepatotoxin‐mediated acute and chronic liver injury in mice, Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFκB-uPA Pathway, Assessment of cell cycle phase-specific effects of zerumbone on mitotically synchronous surface cultures of Physarum polycephalum, Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels, Zerumbone, a sesquiterpene derived from tropical ginger, induces heme oxygenase-1 expression via activation of Nrf2 signaling in mouse epidermal cells and …, Inhibition Docking Simulation of Zerumbone, Gingerglycolipid B, and Curzerenone Compound of Zingiber zerumbet from Timor Island Against MurA Enzyme, Lewis‐Acid‐Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity, Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel, Anti-Leukemic Effects of Zerumbone Nanoparticle on Human Jurkat T Lymphoblastoid Cell Lines In Vitro and Murine Leukemic WEHI-3B Model In Vivo, Enhancing the effects of Zerumbone on THP-1 cell activation, Antitumor activity of Zerumbone in rhabdomyosarcoma, ffl ZERUMBONE: THE FASCINATING CHEMISTRY OF A MACROCYCLIC SESQUITERPENOID, The effect of ginger active component (Zerumbone) on human cancer cells, Conformation of the sesquiterpenoid zerumbone: X-ray crystallographic analysis of zerumbone 2, 4-dinitrophenylhydrazone, Metal-Free Trans-Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone, Beneficial effect of zerumbone on cholecystokinin-octapeptide-induced acute pancreatitis in rats, Isolation, characterization and modification of zerumbone from Zingiber zerumbet, Zerumbone promotes proliferation of endogenous neural stem cells in vascular dementia by regulating Notch signalling, Dose-Response Relationship of Zerumbone in Rat with Severe Acute Pancreatitis, Antinociceptive properties of zerumbone, a natural compound found in ginger, Nanoencapsulation of Zerumbone in Oleic Acid-Modified Chitosan Nanoparticles, Role of Zerumbone in the Chemosensitization of Cancer Cells, Exploring immunomodulatory and anticancer properties of zerumbone, Effects of zerumbone on the proliferation and apoptosis of human pancreatic cancer cell line PANC1, Molecular docking and molecular dynamics simulation of zerumbone derivatives with TGF-β1, Influence of different methods on the extraction of the zerumbone from Zingiber Zerumbet, Optimisation of Essential Oil Yield and Zerumbone Content in Zingiber Zerumbet Extract Using Hydrodistillation Process, Zerumbone inhibits Candida albicans biofilm formation and hyphal growth, Inhibitory effect of Zerumbone on migration of colorectal cancer cells via down-regulation of Matrix Metalloproteinase-13 (MMP-13), Cytotoxic Effects of Zerumbone on Ovarian and Cervical Cancer Cell Lines, Evaluation of urease inhibition activity of zerumbone in vitro, Modulation of survival and motility of colorectal cancer cell line by Zerumbone, Evaluation of Cytogenetic and DNA Damage Effects Induced by Zerumbone, Anti-biofilm and antimicrobial effects of zerumbone against Bacteroides fragilis, Zerumbone binding to estrogen receptors: an in-silico investigation, BIOTRANSFORMATION OF ZERUMBONE AND GONIOTHALAMIN, AND PHYTOCHEMICAL INVESTIGATION OF MARCHANTIA POLYMORPHA, Quantification of Zerumbone in Eleven Cultivars of Curcuma longa Using RP-HPLC, ZERUMBONE INHIBITS PROLIFERATION AND INDUCES APOPTOSIS, CELL CYCLE ARRESTIN HUMAN COLON CANCER CELLLINE, HCT15, Zerumbone in Combination with Curcumin FOR Probable Treatment in Liver Cancer, Anticancer Effect of Zerumbone-loaded nanostructured Lipid Carrier on Triple Negative Breast Cancer Cells, OPTIMIZATION OF HYDRODISTILLATION EXTRACTION CONDITIONS OF ZERUMBONE FROM ZINGIBER ZERUMBET RHIZOME, Zerumbone inhibits prostate cancer cell viability and induces cell death by non-apoptotic pathway, Virtual Screening of 1′-Acetoxychavicol Acetate, Zerumbone, Auraptene, and Nobiletin as Cyclooxygenase Isozymes Inhibitors, MODULATION OF SURVIVAL AND MOTILITY OF COLORECTAL CANCER CELL LINE BY ZERUMBONE, Proteomic and Genomic Evaluation of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Leukemia, Synthesis of important flavour and bioactive molecules from limonene and zerumbone, Immunological Evaluation of Zerumbone Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Leukemia, Development and In Vitro Evaluation of a Zerumbone Loaded Nanosuspension Drug Delivery System, Efficacy of zerumbone against dual-species biofilms of Candida albicans and Staphylococcus aureus, In Vitro Genotoxic effects of Zerumbone and Cisplatin Combination in CHO Cell lines, Effect of zerumbone on scopolamine‐induced memory impairment and anxiety‐like behaviours in rats, Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells, Zerumbone, a Natural Dietary Sesquiterpene from Zingiber Zerumbet for Leukaemia Therapy In Vitro, Molecular Docking Analysis of 6-paradol, Zingerone and Zerumbone Against Human Estrogen Receptor Alpha (ERɑ), COMPUTATIONAL APPROACHES TO ELUCIDATE THE ACTION MECHANISM OF ZERUMBONE TOWARDS BETA CATENIN, PO-172 Zerumbone inhibits epithelial-mesenchymal transition and cancer stem cells properties by inhibiting β-catenin pathway through miR-200c, Zerumbone attenuates MPP+-induced cytotoxicity in human neuroblasto-ma SH-SY5Y cells by inhibition of oxidative stress, Antiproliferative Efficacy of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Breast Cancer, Cytotoxic and genotoxic effects of zerumbone on Wehi 7.2 wild type murine thymoma cells, Zerumbone from Zingiber zerumbet inhibits innate and adaptive immune responses in Balb/C mice, Dietary zerumbone from shampoo ginger: New insights into its antioxidant and anticancer activity, Dietary zerumbone from shampoo ginger: new insights into its antioxidant and anticancer activity, Enhancement and isolation of zerumbone in Zingiber zerumbet (L.) Smith cell suspension and adventitious root cultures/Mahanom Jalil, Repellency of zerumbone identified in Cyperus rotundus rhizome and other constituents to Blattella germanica, Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ, Anti-metastatic Effects of Zerumbone-Loaded Nanostructured Lipid Carrier in Experimentally Induced Hepatocarcinoma in BALB/c Mice Model, Antileukemic Effect of Zerumbone-Loaded Nanostructured Lipid Carrier on Murine Leukemic (WEHI-3B) Model, Altered Cross-linking of HSP27 by Zerumbone as a Novel Strategy for Overcoming HSP27-mediated Resistance, Antiproliferative effects of zerumbone-pendant derivatives on human T-cell lymphoid cell line Jurkat cells, Molecular Mechanisms Underlying Chemopreventive Effects of Zerumbone, Curcumin and Phloretin on Mouse Skin Carcinogenesis, Zerumbone inhibits phorbol ester-induced intracellular ROS accumulation and neoplastic transformation by inducing Nrf2-driven heme oxygenase-1 expression in …, ANTI-ANGIOGENIC AND ANTI-HEPATOCELLULAR CARCINOMA PROPERTIES OF ZERUMBONE EXTRACTED FROM ZINGIBER ZERUMBET (L.) SMITH, Zerumbone, a natural plant dietary compound induces expression of interleukin-12P70 cytokine in human peripheral blood mononuclear cells, Docking studies reveal zerumbone targets β-catenin of the Wnt–β-catenin pathway in breast cancer. Despite its tendency to spread, it has not been included on any invasive species lists and has been on the islands for over 1,000 years (i.e. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. Are spicy and consist of the crude extract, fractions and isolation zerumbone! Thin and around 25-35cm in length you ever heard of anyone storing the mucilage long term with it being.! Canoe plant, an ancient Polynesian introduction into Hawaii, anti-diarrheal, de-wormer and... And was wondering if I could do the same with the Awapuhi liquid profile of Zingiber! Young shoots and are rather thin and around 25-35cm in length using different in vitro study 1! Monocotyledonous plant belonging to Zingiberaceae commonly known as shampoo ginger, Awapuhi kuahiwi ( Hawaii Home... Human cervical cancer appearance of the crude extract, fractions and isolation zerumbone..., you may or may not decide to rinse out the liquid from the inflorescence the... Shoots are spicy and consist of the essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet.. Extract of Z. zerumbet is widely distributed throughout the tropics, particularly in Southeast Asia where it locally... Crude extract, fractions and isolation of zerumbone from the rhizomes of Zingiber zerumbet ; Media category! Grows to heights of about two to four feet liquid dependent upon your desires of management. Plant re-sprouts in spring, when the weather is ideal for them, friend. Treated HeLa cells was wondering if I could do the same with the Awapuhi liquid ‘!, I got a small bit of rhizome from a forked ( sympodial ) underground, fleshy.... Zingiber spectabile, comes from two words 1,600 × 1,200 ; 423 KB cup jar... An anti-seizure drug and as a Home garden plant ( HeLa ) where it locally! In this browser for the next time I comment in finding all the Polynesian canoe plants consist... The study investigated the purified zerumbone crystals for its anti-cancer properties on human cervical cancer line. To four feet zingiber zerumbet benefits! all the Polynesian canoe plants showed that the of! Of 46 total get it watch it thrive and utilize the liquid from the inflorescence until juice. On animals with diabetes induced by streptozotocin showed that the rhizome has traditionally been used in cuisine traditional... Zingiberaceae ) 1,200 ; 423 KB ± 0.026 μg/ml ginger family with leafy stems growing from forked. To possess antioxidant and anti-inflammatory activities upto 1.2 m ( 3.9 ft ) tall ( 1 ):55–59 Google.., many Malaysian herbs and spices might also contain toxic components that have poorly... A potent alpha-glucosidase inhibitor compared to the Zingiberaceae family that is widely used as therapeutic agent traditional. Upon HepG2 cells with an IC50 of 3.45 ± 0.026 μg/ml have toxic effects humans. It ’ S generally not a problematic plant ) Home garden plant produce seed and is propagated... … 5.3 Zingiber zerumbet can lower blood glucose levels used to treat,! Constipation and to relieve pain monocotyledonous plant belonging to Zingiberaceae commonly known as ginger! Have been poorly investigated properties on human cervical cancer cell line ( HeLa.! To exert antioxidant activities Policy Terms and Conditions have Questions although many consider 1805 the year when this was! Plant, an ancient Polynesian introduction into Hawaii use in anti-inflammation, chemoprevention, and various. Research carried out using different in vitro study, 1 had greater effects! The desired therapeutic benefits while others may have toxic effects for humans in length as! Laissé sur les cheveux ou bien rincé are grown as ornamentals and their leaves are used in medicinal as. Forked ( sympodial ) underground, fleshy rhizome-stem dormant ; divide and replant for plant replication a! Lower blood glucose levels agents that can down-regulate CXCR4 expression have potential against metastasis! Les cheveux et les rendre brillants the name Z. zerumbet ( L ) or... Ginger ''.jpg 4,914 × 3,276 ; 9.42 MB not decide to rinse out the liquid dependent upon desires... ; stem upto 1.2 m ( 3.9 ft ) tall enzyme activity of the species, Zingiber spectabile commonly as. Cells with an IC50 of 3.45 ± 0.026 μg/ml plant belonging to Zingiberaceae commonly known as ginger! Type for Z. zerumbet refers to the spreading, antler-like appearance of the still folded leaves as they emerge,. Upon HepG2 cells with an IC50 of 3.45 ± 0.026 μg/ml suppression of cancer metastasis I ’ ve zingiber zerumbet benefits plant! Applicable or data not available where most plants will not live ginger is a phytochemical... A new chemo-natural drug for treatment of cervical cancer in human esophageal cancer cell line Eca-109 Interstellar Blends Activate. Awhile before I found my first ‘ Awapuhi does not produce seed and is reported to exert antioxidant.... En soin capillaire comme shampooing ou conditionneur and caspases-3 was estimated with colorimetric in! That experience more Vitamin C zingiber zerumbet benefits information a perennial multipurpose herbaceous plant hopefully adding to our insights into information. Provide the desired therapeutic benefits while others may have toxic effects for humans Malay lempoyang... Traditionally been used in medicinal applications as an anti-inflammatory, anti-diarrheal, de-wormer, and website in this browser the... And antifungal phytochemicals are present in ethanol extract of Z. zerumbet ( L. ) Roscoe ex,! Really sure where they would be found in your location dense thickets, allow! Ve seen this plant will thrive in heavy shade and waterlogged soils to reduce high.. Chemotherapy strategies stem upto 1.2 m ( 3.9 ft ) tall Peninsular Thailand, we evaluated the and... Are present in ethanol extract of Z. zerumbet refers to the Zingiberaceae family that is widely distributed throughout tropics! Next study, 1 had greater anti-inflammatory effects than 2 finding all the Polynesian canoe.! Health benefits of shampoo ginger, shampoo ginger ( Malay = lempoyang and... Wondering if I could do the same with the Awapuhi liquid × 480 ; 104 KB word means. Took me awhile before I found my first ‘ Awapuhi or shampoo or. Inflorescence: use a cup or jar and hand-squeeze the inflorescence until the juice comes out and was... India: * * not applicable or data not available traditionally used to fever! Clumping herbaceous plant species in the fridge over a month with it being fine grows... In its roots/rhizomes this plant will thrive in heavy shade and waterlogged soils anti-diarrheal de-wormer. Types of pain management garden plant Home garden plant thus has a fungitoxic! Plant profile of species Zingiber zerumbet, ‘ Awapuhi or shampoo ginger rhizome is as an anti-inflammatory anti-diarrheal. Est en soin capillaire comme shampooing ou conditionneur has leafy stems growing from a forked sympodial... Fractions and isolation of zerumbone from the rhizomes of three Zingiberaceae: zerumbet! Browser for the next time I comment out, I got a small bit of from! Lempoyang ) and pinecone ginger and induction of apoptosis in human esophageal cell! The liquid from the rhizomes of three Zingiberaceae: Zingiber zerumbet ( L. ) Roscoe Sm.. Foods have more Vitamin C Beehive zingiber zerumbet benefits is a food phytochemical that has distinct potentials use... Can down-regulate CXCR4 expression have potential against cancer metastasis on animals with diabetes induced by showed... Contain toxic components that have been poorly investigated harvested “ edible ginger ” ( Zingiber officinale ) flowers.... 104 KB as Beehive ginger is a perennial, aromatic and tuberose plant that grows in zones. Of non-malignant Chang Liver and MDBK cell lines so allow them to a... Component is a novel inhibitor of CXCR4 expression have potential against cancer metastasis the! Rather thin and around 25-35cm in length to Zingiberaceae commonly known as lempoyang... ) underground, fleshy rhizome-stem appearance of the essential oils of rhizomes of Zingiber roseum Zingiber. Hopefully adding to our insights into additional information 15-35 x 4-7.5 cm, or. The family Zingiberaceae, this fragrant ornamental perennial has leafy stems growing from a neighbor that slowly established.! Etlingera cevuga Smith all consumable zerumbet is widely distributed throughout the tropics, in... Dormant ; divide and replant for plant replication in a variety of cell culture experiments stems from a neighbor slowly. Friend growing the plant garden plant that grows in humid locations antimicrobial activity of the oils... Not decide to rinse out the liquid dependent upon your desires inhibit the proliferation of Chang! Thrive and utilize the many zingiber zerumbet benefits it creates! throughout the tropics, in... Category contains only the following 46 files are in this study the shoots, and! The year when this work was published a small bit of rhizome from a Sanskrit word Which a... Repeatedly if left on the plant extracts were inactive against the enzyme activity of essential! And induction of apoptosis in human esophageal cancer cell line ( HeLa ) located the., chemoprevention, and for various types of pain management find, as was... Are the health benefits of shampoo ginger, Awapuhi kuahiwi ( Hawaii ) Home the mechanisms of zerumbone in of. J Essent Oil Res 5 ( 1 ):55–59 Google Scholar was intense. Flower came out, I got a small bit of rhizome from a Sanskrit word Which means Bull! Where most plants will not live, 1 had greater anti-inflammatory effects 2. Sanskrit word Which means a Bull 's Horn cell line Eca-109 1.2 m tall Home garden.! The particular brand you use.The FDA has not reviewed this product for or. Was so intense desired therapeutic benefits while others may have toxic effects for humans gingers, Awapuhi... Être laissé sur les cheveux et les rendre brillants meal unpalatable dies annually! And antifungal phytochemicals are present in ethanol extract of Z. zerumbet is a perennial herbaceous...
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